Traveling southbound on I-95, take exit 84S bearing left onto CT-32 E toward downtown New London. CT-32 E becomes Eugene O'Neill Drive. At second light, turn right onto Governor Winthrop Boulevard. ISAAC is at 190 Governor Winthrop Boulevard, across from the Raisson Hotel. Entrance in rear.

Traveling northbound on on I-95, take exit 83 toward Norwich, CT-32, and downtown New London. Stay straight at light at end of ramp to go onto Huntington Street. Turn left after 0.6 mile onto Governor Winthrop Boulevard. ISAAC is at 190 Governor Winthrop Boulevard, across from the Raisson Hotel. Entrance in rear.